Questions about example sentences with, and the definition and usage of "Lefty"

A: "Lefty" has two meanings:
1) a left-handed person (not insulting)
2) an insult meaning "a liberal person" or "a Democrat," meaning a politically left or politically liberal person.

"Inner-city" means "from a big city," or maybe "from the middle part of the city." This phrase is often used as an insult to mean "the poor part of the city," or "the part of the city with many immigrants and minorities."

In America: minorities, immigrants, and people from big cities tend to be more politically liberal (left), while White people and people from rural areas tend to be more conservative (right). So, "inner-city lefty" is a phrase that a conservative person might use to insult a liberal person.

A: left handed, a person who writes with their left hand (or when used for a guitar, a person who strums the guitar with their left hand)

A: Without context, I interpret that as a person who uses their left hand for most of the things they do, like write, throw a ball, etc. Their left hand is their dominant hand.

A: Alguien que usa su mano izquierda

A: "By nature" sounds a little weird. It's fine to just put "Im originally a lefty". Everything else is perfect.

A: http://deep.mastersfamily.org/2009-10/why-are-left-handed-people-called-southpaws/

A: It sounds natural, but "lefty" is informal/slang and the meaning may not be clear to everyone. It's better to say "I'm left-handed" in most cases.